ichor.bio授權(quán)代理——上海起發(fā)

更新時(shí)間：2024-04-12

點(diǎn)擊次數(shù)：695

ichor.bio

鏈接：https://www.ichor.bio/about/

ichorbio總部位于牛津，致力于開發(fā)最高質(zhì)量的試劑，成為研究級(jí)生物仿制藥和體內(nèi)抗體的最大供應(yīng)商，推動(dòng)科學(xué)研究的進(jìn)步。ichorbio目前可提供140多種價(jià)格j具競爭力的體內(nèi)研究抗體及相關(guān)同型對(duì)照抗體。同時(shí)，新增免疫檢查點(diǎn)分子相關(guān)產(chǎn)品、科研用生物仿制藥單克隆抗體、HLA-DR抗體、HLA-DQ抗體、體內(nèi)抗體標(biāo)記試劑盒，涵蓋癌癥研究、心血管研究、細(xì)胞生物學(xué)、表觀遺傳學(xué)和核信號(hào)、免疫學(xué)、微生物學(xué)、神經(jīng)科學(xué)、信號(hào)轉(zhuǎn)導(dǎo)和干細(xì)胞研究等各個(gè)研究領(lǐng)域，以滿足科學(xué)探索的各種需求。

癌癥

Cancer

心血管

Cardiovascular

細(xì)胞生物學(xué)

Cell Biology

免疫學(xué)

Immunology

微生物學(xué)

Microbiology

神經(jīng)科學(xué)

Neuroscience

信號(hào)轉(zhuǎn)導(dǎo)

Transduction

標(biāo)簽和細(xì)胞標(biāo)志物

Tags & Cell Markers

干細(xì)胞

Stem Cells

使用ichorbio產(chǎn)品發(fā)表的部分文獻(xiàn)：

發(fā)表年份	文章標(biāo)題	期刊名稱	作者	引用的ichorbio產(chǎn)品
2023	Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity.	Cell Stem Cell	Gravina et al.	ICH4002
2023	Blinatumomab Redirects Donor Lymphocytes against CD19+ Acute Lymphoblastic Leukemia without Relevant Bystander Alloreactivity after Haploidentical Hematopoietic Stem Cell Transplantation.	Int. J. Mol. Sci.	Mancusi et al.	ICH5025
2023	A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors	Front Immunol.	Iadonato et al.	ICH4002
2023	One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade	bioRxiv	Xu et al.	IHC1132
2023	A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity	Journal of Experimental & Clinical Cancer Research	Lee et al.	ICH5015
2023	Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer	Journal for ImmunoTheraphy of Cancer	Travelli et al.	ICH2248
2023	M0bile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies	Analytical Chemistry	Narsimhan et al.	ICH4011, ICH4009, ICH4019
2023	Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation	Journal of Nanobiotechnology	Cao et al.	ICH1077, ICH1042, and ICH1043
2023	Aconite aqueous extract inhibits the growth of hepatocellular carcinoma through CCL2-dependent enhancement of natural killer cell infiltration	Journal of Integrative Medicine	Yang et al.	ICH1128UL
2023	WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis	Cytokine	Yuan et al.	ICH1026

FAQ

1.低內(nèi)毒素和超低內(nèi)毒素有什么區(qū)別？

答：ichorbio生產(chǎn)兩種用于體內(nèi)使用的格式：低內(nèi)毒素和超低內(nèi)毒素。超低格式具有更高的純度，更低的內(nèi)毒素，更低的聚集，并且經(jīng)過了與將要使用的動(dòng)物相關(guān)的病原體測(cè)試。

2.抗體如何儲(chǔ)存？效期多久？

答：遵循我們數(shù)據(jù)表上列出的存儲(chǔ)信息。只有在存儲(chǔ)溫度正確時(shí)才保證一年的使用效期。

3.抗體溶液中發(fā)現(xiàn)有沉淀物是什么？

答：環(huán)境條件，如溫度變化、凍結(jié)/解凍、運(yùn)輸過程中的搖晃以及長期存儲(chǔ)可能導(dǎo)致抗體溶液出現(xiàn)沉淀或絮塊。絮塊通常是緩沖鹽從溶液中沉淀出來或者一小部分蛋白質(zhì)聚集。如果輕輕地反復(fù)倒置小瓶，應(yīng)該可以去除沉淀。如果不能去除，我們建議通過過濾或離心來去除絮塊。

對(duì)于過濾，建議使用無菌的0.2μM過濾器。對(duì)于離心，我們建議將抗體溶液轉(zhuǎn)移到無菌離心管中（不要在提供的冷凍瓶中離心），并在10k rpm下離心5分鐘。更建議使用過濾而不是離心，因?yàn)殡x心可能使樣品發(fā)熱的時(shí)間比過濾的方式長，而過濾則可以非?？焖俚赝瓿?。無論選擇哪種方法，都應(yīng)使用無菌過濾器、注射器、管子等，并在生物安全柜中操作，以確保溶液保持無菌。此外，使用這些方法可以去除沉淀而不會(huì)有顯著的蛋白質(zhì)損失。如果在離心或過濾后擔(dān)心損失，您可以檢查離心或過濾后的蛋白質(zhì)濃度，并將其與提供的CoA上的濃度進(jìn)行比較。

4.稀釋抗體的最佳方法是什么？

答：可以使用與抗體配方w全相符的無菌1*PBS。在稀釋時(shí)，建議使用冷緩沖液，并通過在生物安全柜中操作以及使用無菌移液管頭、管子、注射器和緩沖液來保持無菌。應(yīng)避免將抗體稀釋到工作濃度并在4℃以上存儲(chǔ)超過一天。

更多其它產(chǎn)品詳情請(qǐng)查詢ichorbio網(wǎng)站或咨詢ichorbio中國代理上海起發(fā)。

下圖為ichorbio公司授權(quán)上海起發(fā)作為中國區(qū)域代理的授權(quán)書。

ichorbio熱賣產(chǎn)品

貨號(hào)	產(chǎn)品名稱	規(guī)格	品牌
ICH1132-100mg	Anti-Mouse PD-1 In Vivo Antibody – Low Endotoxin (RMP1-14)	100mg	ichorbio
ICH5025-1mg	Blinatumomab Biosimilar - Research Grade [ICH5025]	1mg	ichorbio
ICH1132-50mg	Anti-Mouse PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14)	50mg	ichorbio
ICH1114-5mg	Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin (IK22/5)	5mg	ichorbio
ICH5056-20mg	Abciximab Biosimilar - Research Grade	20mg	ichorbio
ICH1009-25mg	Bulk anti-Human CD14 antibody (UCHM-1)	25mg	ichorbio
ICH2255-25mg	Bulk Human IgG2 Isotype Control (IB2)	25mg	ichorbio
ICH5025-5mg	Blinatumomab Biosimilar - Research Grade	5mg	ichorbio
ICH4002-1mg	Alemtuzumab Biosimilar - Research Grade	1mg	ichorbio
ICH1002-25mg	Bulk anti-Human CD3 antibody (UCHT-1)	25mg	ichorbio
ICH1002-5mg	Bulk anti-Human CD3 antibody (UCHT-1)	5mg	ichorbio
ICH2249UL-5mg	Mouse IgG3 Isotype Control for In Vivo - Ultra Low Endotoxin (MG3-35) [ICH2249UL]	5mg	ichorbio
ICH5056-1mg	Abciximab Biosimilar - Research Grade	1mg	ichorbio
ICH1086-5mg	Anti-Mouse PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2)	5mg	ichorbio
ICH1075-5mg	Anti-Mouse CD155 In Vivo Antibody – Low Endotoxin (4.24)	5mg	ichorbio
ICH1015-25mg	Bulk anti-Human CD56 antibody (ERIC-1)	25mg	ichorbio
ICH5025-0.5mg	Blinatumomab Biosimilar - Research Grade [ICH5025]	0.5mg	ichorbio
ICH2254-100mg	Bulk Human IgG1 Isotype Control (IB1) [ICH2254]	100mg	ichorbio
ICH1086-100mg	Anti-Mouse PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2)	100mg	ichorbio
ICH1002-50mg	Bulk anti-Human CD3 antibody (UCHT-1)	50mg	ichorbio
ICH1002-100mg	Bulk anti-Human CD3 antibody (UCHT-1)	100mg	ichorbio
ICH1025-5mg	Bulk anti-Human HLA-DQ antibody (1a3)	5mg	ichorbio
ICH1024-5mg	Bulk anti-Human HLA-DP antibody (B7/21)	5mg	ichorbio
ICH1183-100mg	Mouse anti-Mouse PD-L1 antibody (10F.9G2) [ICH1183]	100mg	ichorbio
ICH2254LALA-5mg	Human IgG1 Isotype Control (IB1) LALA	5mg	ichorbio
ICH5070-1mg	Enfortumab Biosimilar - Research Grade	1mg	ichorbio
ICH1042-1mg	Anti-Mouse CD4 In Vivo Antibody - Low Endotoxin (GK1.5)	1mg	ichorbio
ICH2250-5mg	Mouse IgG2b Isotype Control for In Vivo – Low Endotoxin (MPC-11)	5mg	ichorbio
ICH1130-25mg	Anti-Mouse, Human CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2)	25mg	ichorbio
ICH1172-25mg	Bulk anti-Human CCR5 antibody (HEK/1/85a/7a)	25mg	ichorbio
ICH1028-25mg	Bulk anti-Human CD119 antibody (GIR 208)	25mg	ichorbio
ICH4014-0.1mg	Ado-trastuzumab emtansine Biosimilar - Research Grade	0.1mg	ichorbio
ICH1094-25mg	Anti-Mouse CD120a In Vivo Antibody - Low Endotoxin (55R-170)	25mg	ichorbio
ICH1117-25mg	Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147)	25mg	ichorbio
ICH1023-25mg	Bulk anti-Human MHC Class I antibody (W6/32)	25mg	ichorbio
ICH1007-25mg	Bulk anti-Human CD11b antibody (ICRF44)	25mg	ichorbio
ICH1114-25mg	Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin (IK22/5)	25mg	ichorbio
ICH1011-25mg	Bulk anti-Human CD19 antibody (SJ25-C1)	25mg	ichorbio
ICH1040-25mg	Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (500A2)	25mg	ichorbio
ICH1032-25mg	Bulk anti-Human iNKT cell antibody (6B11)	25mg	ichorbio
ICH1196-25mg	Anti-Mouse CD134 In Vivo Antibody (OX-86) - Low Endotoxin	25mg	ichorbio
ICH1092-25mg	Anti-Mouse Dendritic Cells In Vivo Antibody - Low Endotoxin (33D1)	25mg	ichorbio
ICH1122-25mg	Anti-Mouse IFNAR1 In Vivo Antibody - Low Endotoxin (MAR1-5A3)	25mg	ichorbio
ICH1021-25mg	Bulk anti-Human EGFR antibody (EGFR.1)	25mg	ichorbio
ICH1206-25mg	Anti-Mouse IL-21R In Vivo Antibody (4A9) - Low Endotoxin	25mg	ichorbio
ICH2254-5mg	Bulk Human IgG1 Isotype Control (IB1)	5mg	ichorbio
ICH4005-20mg	Eculizumab Biosimilar - Research Grade	20mg	ichorbio
ICH1137-25mg	Anti-Mouse TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7)	25mg	ichorbio
ICH1076-5mg	Anti-Mouse CD172a In Vivo Antibody - Low Endotoxin (P84)	5mg	ichorbio
ICH5025-0.1mg	Blinatumomab Biosimilar - Research Grade	0.1mg	ichorbio

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